Research Topic

density functional

20 publications exploring this topic

2025

2025

AIQM3: Targeting Coupled-Cluster Accuracy with Semi-Empirical Speed Across Seven Main Group Elements

Chen Y., Hou Y., Zubatyuk R., Isayev O., Dral P. O.

(2025)

Quantum Chemistry
Ml Potentials
Drug Discovery

The AIQM series methods are successful neural network-based models that target coupled-cluster accuracy while maintaining high robustness and transferability across various tasks by leveraging Δ-learning.

DOI

2024

2024
cited17

AIMNet2: A Neural Network Potential to Meet your Neutral, Charged, Organic, and Elemental-Organic Needs

Anstine D., Zubatyuk R., Isayev O.

(2024)

Ml Potentials
Quantum Chemistry

Machine learned interatomic potentials (MLIPs) are reshaping computational chemistry practices because of their ability to drastically exceed the accuracy-length/time scale tradeoff.

DOI
2024
cited17

AIMNet2: A Neural Network Potential to Meet your Neutral, Charged, Organic, and Elemental-Organic Needs

Anstine D., Zubatyuk R., Isayev O.

(2024)

Ml Potentials

Machine learned interatomic potentials (MLIPs) are reshaping computational chemistry practices because of their ability to drastically exceed the accuracy-length/time scale tradeoff.

DOI

2023

2023
cited27

AIMNet2: A Neural Network Potential to Meet your Neutral, Charged, Organic, and Elemental-Organic Needs

Anstine D., Zubatyuk R., Isayev O.

(2023)

Ml Potentials

Machine learned interatomic potentials (MLIPs) are reshaping computational chemistry practices because of their ability to drastically exceed the accuracy-length/time scale tradeoff.

DOI

2021

2021
cited11

Active Learning in Bayesian Neural Networks for Bandgap Predictions of Novel Van der Waals Heterostructures

Fronzi M., Isayev O., Winkler D. A., Shapter J. G., Ellis A. V., Sherrell P. C., Shepelin N. A., Corletto A., Ford M. J.

Advanced Intelligent Systems, 3 (2021)

Experiment Automation

The bandgap is one of the most fundamental properties of condensed matter.

DOI
2021
cited25

Machine learned Hückel theory: Interfacing physics and deep neural networks

Zubatiuk T., Nebgen B., Lubbers N., Smith J. S., Zubatyuk R., Zhou G., Koh C., Barros K., Isayev O., Tretiak S.

The Journal of Chemical Physics, 154 (2021)

Quantum Chemistry

The Hückel Hamiltonian is an incredibly simple tight-binding model known for its ability to capture qualitative physics phenomena arising from electron interactions in molecules and materials.

DOI
2021
cited94

Teaching a neural network to attach and detach electrons from molecules

Zubatyuk R., Smith J. S., Nebgen B. T., Tretiak S., Isayev O.

Nature Communications, 12 (2021)

Ml Potentials
Reactions Reactivity
Drug Discovery
Quantum Chemistry

Abstract Interatomic potentials derived with Machine Learning algorithms such as Deep-Neural Networks (DNNs), achieve the accuracy of high-fidelity quantum mechanical (QM) methods in areas traditionally dominated by empirical force fields and allow performing massive simulations.

DOI
2021
cited3

Teaching a Neural Network to Attach and Detach Electrons from Molecules

Zubatyuk R., Smith J., Nebgen B. T., Tretiak S., Isayev O.

(2021)

Ml Potentials
Reactions Reactivity
Drug Discovery
Quantum Chemistry

Physics-inspired Artificial Intelligence (AI) is at the forefront of methods development in molecular modeling and computational chemistry.

DOI

2020

2020
cited14

High Throughput Screening of Millions of van der Waals Heterostructures for Superlubricant Applications

Fronzi M., Tawfik S. A., Ghazaleh M. A., Isayev O., Winkler D. A., Shapter J., Ford M. J.

Advanced Theory and Simulations, 3 (2020)

AbstractThe screening of novel materials is an important topic in the field of materials science.

DOI
2020
cited212

The ANI-1ccx and ANI-1x data sets, coupled-cluster and density functional theory properties for molecules

Smith J. S., Zubatyuk R., Nebgen B., Lubbers N., Barros K., Roitberg A. E., Isayev O., Tretiak S.

Scientific Data, 7 (2020)

Ml Potentials
Quantum Chemistry
Experiment Automation

Abstract Maximum diversification of data is a central theme in building generalized and accurate machine learning (ML) models.

DOI
2020
cited2

The ANI-1ccx and ANI-1x Data Sets, Coupled-Cluster and Density Functional Theory Properties for Molecules

Smith J. S., Zubatyuk R., Nebgen B. T., Lubbers N., Barros K., Roitberg A., Isayev O., Tretiak S.

(2020)

Quantum Chemistry
Ml Potentials
Experiment Automation

Maximum diversification of data is a central theme in building generalized and accurate machine learning (ML) models.

DOI
2020
cited2

The ANI-1ccx and ANI-1x Data Sets, Coupled-Cluster and Density Functional Theory Properties for Molecules

Smith J. S., Zubatyuk R., Nebgen B. T., Lubbers N., Barros K., Roitberg A., Isayev O., Tretiak S.

(2020)

Quantum Chemistry
Ml Potentials
Experiment Automation

Maximum diversification of data is a central theme in building generalized and accurate machine learning (ML) models.

DOI
2020
cited7

Teaching a Neural Network to Attach and Detach Electrons from Molecules

Zubatyuk R., Smith J., Nebgen B. T., Tretiak S., Isayev O.

(2020)

Ml Potentials
Reactions Reactivity
Drug Discovery
Quantum Chemistry

Physics-inspired Artificial Intelligence (AI) is at the forefront of methods development in molecular modeling and computational chemistry.

DOI

2019

2019

The ANI-1ccx and ANI-1x Data Sets, Coupled-Cluster and Density Functional Theory Properties for Molecules

Smith J. S., Zubatyuk R., Nebgen B. T., Lubbers N., Barros K., Roitberg A., Isayev O., Tretiak S.

(2019)

Quantum Chemistry
Ml Potentials
Experiment Automation

Maximum diversification of data is a central theme in building generalized and accurate machine learning (ML) models.

DOI

2018

2018
cited80

Efficient Prediction of Structural and Electronic Properties of Hybrid 2D Materials Using Complementary DFT and Machine Learning Approaches

Tawfik S. A., Isayev O., Stampfl C., Shapter J., Winkler D. A., Ford M. J.

Advanced Theory and Simulations, 2 (2018)

Quantum Chemistry
Experiment Automation

Abstract There are now, in principle, a limitless number of hybrid van der Waals (vdW) heterostructures that can be built from the rapidly growing number of 2D layers.

DOI
2018

Efficient prediction of structural and electronic properties of hybrid 2D materials using complementary DFT and machine learning approaches

Tawfik S., Isayev O., Stampfl C., Shapter J., Winkler D., Ford M. J.

(2018)

Quantum Chemistry
Experiment Automation

There are now, in principle, a limitless number of hybrid van der Waals heterostructures that can be built from the rapidly growing number of two-dimensional layers.

DOI
2018

Efficient prediction of structural and electronic properties of hybrid 2D materials using complementary DFT and machine learning approaches

Tawfik S., Isayev O., Stampfl C., Shapter J., Winkler D., Ford M. J.

(2018)

Quantum Chemistry
Experiment Automation

There are now, in principle, a limitless number of hybrid van der Waals heterostructures that can be built from the rapidly growing number of two-dimensional layers.

DOI

2011

2011
cited41

Toward robust computational electrochemical predicting the environmental fate of organic pollutants

Sviatenko L., Isayev O., Gorb L., Hill F., Leszczynski J.

Journal of Computational Chemistry, 32, 2195–2203 (2011)

Materials Informatics

AbstractA number of density functionals was utilized for the calculation of electron attachment free energy for nitrocompounds, quinones and azacyclic compounds.

DOI

2007

2007
cited41

Theoretical calculations: Can Gibbs free energy for intermolecular complexes be predicted efficiently and accurately?

Isayev O., Gorb L., Leszczynski J.

Journal of Computational Chemistry, 28, 1598–1609 (2007)

Quantum Chemistry
Ml Potentials

AbstractThe theoretical study has been performed to refine the procedure for calculations of Gibbs free energy with a relative accuracy of less than 1 kcal/mol.

DOI

2004

2004
cited9

Modeling the Gas-Phase Reduction of Nitrobenzene to Nitrosobenzene by Iron Monoxide: A Density Functional Theory Study

Zilberberg I., Ilchenko M., Isayev O., Gorb L., Leszczynski J.

The Journal of Physical Chemistry A, 108, 4878–4886 (2004)

Modeling the Gas-Phase Reduction of Nitrobenzene to Nitrosobenzene by Iron Monoxide: A Density Functional Theory Study.

DOI